High Doses of Vitamin D May Prevent RelapsesIt's no news that vitamin D deficiency might be one of the causes of multiple sclerosis. I guess, then it makes some sense that taking a high dose of vitamin D may help reduce relapses in people with MS, so researchers have attempted to find this out with a small study.
In this study, 25 people with relapsing-remitting multiple sclerosis were given a high dose of vitamin D (14,000 international units, IU, each day for a year) and were compared to 24 people who took a lower dose of vitamin D (1,000 IU a day for a year). In the high-dose group, 16% of the people had a relapse, compared to 40% in the low-dose group. As a bonus, the high dose group reported no side effects from the vitamin D supplement.
The dose given to the high dose group wasn't constant, instead it was increased for 6 months to 40,000 IU, and then decreased. The average dose was 14,000 IU, but it is not known if this is the dose that is most effective. All participants also took a calcium supplement, which is absorbed better with vitamin D.
This is not a call to go dose up on huge doses of Vitamin D. While it is fairly harmless at doses of 600 IU, higher doses can lead to gastrointestinal problems and even kidney damage. The best thing to do is talk to your doctor and have your vitamin D levels in your blood checked (through a simple blood test). Then you can take supplements to boost the level if it seems to make sense.
Up to 10,000iu/daily is known to be a safe upper limit even if you also get plenty of sunshine.劑量多高呢? 原則上, 一天10,000IU(國際單位)為安全的上限, 再加上足夠的曬太陽就已經ok了. 過高的維生素D可能引發其他的疾病(胃腸的或腎臟的問題). 在服用Vit D的同時,請記得一起服用 Ca鈣, 服用鈣片應合併服用VITD更能促進鈣質吸收(對於長期服用類固醇的我們有幫助).