對於許多MS人而言，擁抱能夠催生腦內多巴胺，讓人有愉快的感覺，也是一種療癒方式。
但是多發性硬化症中有一個症狀是：【MS Hug】有人說擁抱太浪漫，描述為【MS Grip Of Death】死亡之抱。
具體的臨床感覺描述如下： 莫名的胃痛 胸悶 吸不到氣 感覺或胸部有帶狀的壓迫痛感 會有肚子或胸部壓迫感覺. 也有灼熱感,刺痛感, 或胸腹被環繞抱住的緊繃感. 我認識的病友中，就有一位是已經壓迫到呼吸困難的情形，甚至影響睡眠，這樣的狀況非常的棘手。因為神經不自主命令肌肉收縮所造成. 所以一但影響到腹部，則腹部肌肉和肋間肌收縮僵硬也會，就形成了MS擁抱。像一個緊箍咒，只是抱在你胸，或腹部。 也因為是神經性的問題，是一種非器質性(器官組織檢察看來沒問題)的病變。 美國國家多發性硬化協會定義: 它是種感覺異常 The National Multiple Sclerosis Society (NMSS) describes this dysesthesia (not normal sensation) as a feeling of constriction around the abdomen or chest. The “huggee” may feel burning, aching, or girdling — not the good feelings associated with a real hug! The MS hug is likely caused by a combination of nerve pain and muscle constriction. Abdominal muscles and the tiny muscles between the ribs may contract and stiffen. 什麼會觸發MS HUG這樣的感覺呢？ 熱天氣，壓力，和疲累勞累。 Heat, stress, and fatigue
這時候你需要
多休息more rest
降溫 Cool off
不要讓自己的體溫再升高to treat a fever that’s increasing your body temperature
如果仔細看的白質剛修改的部分...一已經感覺到用肉眼在每一個人的焦點中間的紅點或線，。與充血的小血管腔...所有這使我們要搜索的疾病在各個容器和其後果的改變的主要原因;病灶內運行的所有容器，而且那些遍歷立即周圍，但仍然完好實質是在慢性炎症的狀態特性。
Rindfleisch E. - “Histologisches詳細祖德grauen變性馮GEHIRN UND ruckenmark”。病理解剖學和生理學的檔案。 1863年; 26：474-483。
鏈接
Sustained stress erodes memory, and the immune system plays a key
role in the cognitive impairment, according to a new study from
researchers at The Ohio State University.
The work in mice could one day lead to treatment for repeated,
long-term mental assault such as that sustained by bullying victims,
soldiers and those who report to beastly bosses, the researchers say.
"This is chronic stress. It's not just the stress of giving a talk
or meeting someone new," said lead researcher Jonathan Godbout,
associate professor of neuroscience at Ohio State.
This is the first study of its kind to establish the relationship
between short-term memory and prolonged stress. In the case of the mice,
that meant repeat visits from a larger, nasty intruder mouse.
Mice that were repeatedly exposed to the aggressive intruder had a
hard time recalling where the escape hole was in a maze they'd mastered
prior to the stressful period.
"The stressed mice didn't recall it. The mice that weren't stressed, they really remembered it," Godbout said.
They also had measurable changes in their brains, including evidence
of inflammation brought on by the immune system's response to the
outside pressure. This was associated with the presence of immune cells,
called macrophages, in the brain of the stressed mice.
The research team was able to pin the short-term memory loss on the inflammation, and on the immune system.
Their work, which appears in The Journal of Neuroscience, builds on previous research substantiating the connections between chronic stress and lasting anxiety.
The impact on memory and confirmation that the brain inflammation is
caused by the immune system are important new discoveries, Godbout
said.
"It's possible we could identify targets that we can treat pharmacologically or behaviorally," he said.
It could be that there are ways to interrupt the inflammation, said
John Sheridan, who worked on the study and is associate director of Ohio
State's Institute for Behavioral Medicine Research.
The mice used in the study are exposed to repeated social defeat -
basically dominance by an alpha mouse - that aims to mimic chronic
psychosocial stress experienced by humans.
Researchers at Ohio State seek to uncover the secrets behind stress
and cognitive and mood problems with a long-range goal of finding ways
to help those who are anxious, depressed and suffer from lasting
problems, including post-traumatic stress disorder.
This new research focused on the hippocampus, a hub of memory and emotional response.
The researchers found that the stressed mice had trouble with
spatial memory that resolved within 28 days. They found that the mice
displayed social avoidance, which measures depressive-like behavior,
that continued after four weeks of monitoring.
And they were able to measure deficits in the development of new neurons 10 days and 28 days after the prolonged stress ended.
When they gave the mice a chemical that inhibited inflammation,
neither the brain-cell problem nor the depressive symptoms went away.
But the memory loss and inflammatory macrophages did disappear.
And that led them to conclude that the post-stress memory trouble is
directly linked to inflammation - and the immune system - rather than
to other damage to the brain. That type of information can pave the way
for immune-based treatments, Godbout said.
"Stress releases immune cells from the bone marrow and those cells
can traffic to brain areas associated with neuronal activation in
response to stress," Sheridan said. "They're being called to the brain,
to the center of memory."
###
The researchers' work was supported by the National Institutes of
Health, the National Institute of Aging and the National Institute of
Dental and Craniofacial Research.
Other Ohio State researchers who worked on the study were Daniel McKim, Anzela Niraula, Andrew Tarr and Eric Wohleb.
CONTACTS: Jonathan Godbout, 614-293-3456; Jonathan.Godbout@osumc.edu John Sheridan, 614-293-3571; John.Sheridan@osumc.edu
Written by: Misti Crane, 614-292-5220; Crane.11@osu.edu
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