探討不同年齡層的多發性硬化症患者 在血管窄化的分部情形

來自意大利的研究贊博尼的研究
Age-related Vascular Differences among Patients Suffering from Multiple Sclerosis
收錄在
Current Neurovascular Research
ISSN (Print): 1567-2026
ISSN (Online): 1875-5739
VOLUME: 11
ISSUE: 1
DOI: 10.2174/1567202610666131125000506 

552多發性硬化症患 受測者中，在仰臥和坐姿這兩個的分別掃描。 有458 （ 83 ％）顯示出有窄化的現象 其中：小於30歲者 （ 110名患者）和 大於 30歲者（ 348例）。年輕患者表比起年紀大的患者 更多較嚴重的頸靜脈窄化現象.

研究人員認為，這種疾病的持續將改變靜脈的血流動力學，並且惡化。 “這是可能的，早期的臨床，藥理和/或侵入性的血管介入可以發揮其效果，而且是必要的 

有全文可以下載.
http://www.ncbi.nlm.nih.gov/pubmed/24274909

 Age-related Vascular Differences among Patients Suffering from Multiple Sclerosis

Author(s): Francesco Ciciarello, Sandro Mandolesi, Aldo Innocente Galeandro, Azzurra Marceca, Michele Rossi, Francesco Fedele, Michele Gesualdo, Francesca Cortese, Annapaola Zito, Francesco Federico, Paolo Livrea, Maria Trojano, Pietro Scicchitano and Marco Matteo Ciccone
Pages 23-30 (8)

Abstract:

The aim of our study was to analyze morphological and functional aspects of cerebral veins by means of ecocolor- Doppler in young (i.e., ≤30 years old) and older (i.e., >30 years old) patients suffering from multiple sclerosis. 552 multiple sclerosis patients were evaluated by means of a dedicated Echo-Color-Doppler support (MyLab Vinco echocolor Doppler System, Esaote), in both supine and sitting positions. 458 (83%) showed alterations in their morphological and functional structures of cerebral veins and were divided in two different groups: 1) ≤30 (110 patients) and 2) >30 years old (348 patients). Young patients showed a statistically significant higher number of both hemodynamically (44% vs. 35%, p<0 .01="" 45="" 65="" a="" and="" as="" blocked="" cervical="" compared="" in="" internal="" jugular="" lower="" non-hemodynamically="" of="" older="" ones.="" outflow="" p="" patients.="" patients="" percentage="" showed="" significant="" stenosis="" the="" to="" veins="" vs.="" young="">30 years old outlined a significantly higher disability degree (Expanded Disability Status Scale score: 5 vs. 3, p<0 .01="" 5="" a="" abnormalities.="" about="" adult="" advanced="" alteration="" alterations="" and="" are="" as="" be="" blocked="" blood="" by="" cells="" cerebral="" clinical="" complex="" confirm="" considerations.="" controls="" could="" damages="" degree.="" degree="" differences:="" differences="" different="" difficult="" disability="" disease.="" disease="" diseases="" div="" due="" duration="" early="" endothelial="" evidenced="" exert="" explain="" flow="" form="" former="" functions="" further="" furthermore="" genesis="" groups="" hemodynamic="" higher="" history="" hydrostatic="" impair="" impairments="" in="" increase="" induce="" induced="" internal="" interventions="" invasive="" it="" jugular="" kind="" latter.="" leading="" may="" months="" more="" morphological="" much="" multiple="" natural="" needed="" nevertheless="" no="" of="" or="" order="" outflow.="" outlined="" p="" patients="" pharmacological="" possible="" pressure="" return="" role="" sclerosis.="" sclerosis="" showing="" skull="" stenosis="" such="" than="" that="" the="" therefore="" this="" through="" to="" trials="" turn="" vascular="" vein="" veins="" venous="" vertebral="" vessels="" vs.="" walls:="" was="" well="" which="" worsen="" young="" younger.="">

 

探討不同年齡層的多發性硬化症患者 在血管窄化的分部情形